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By P. V. Sivakumar, N. S. Williams, I. J. Puzanov, J. D. Schatzle, M. Bennett, V. Kumar (auth.), Sudhir Gupta, Alan Sher, Rafi Ahmed (eds.)

The most recent advancements within the region of microbial immunity are explored and defined during this well timed quantity, together with new conceptual frameworks for the processing and presentation of peptides and nonpeptide antigens from microbes to T cells. Such experimental types were instrumental in defining many of the pathways for producing protecting immune responses opposed to microbes.
different issues lined contain: DAP 12, CD4+, Th1 and Th2 Cells, HIV an infection, fusion, and tropism, and vaccine improvement.

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Mechanisms of Lymphocyte Activation and Immune Regulation VII: Molecular Determinants of Microbial Immunity

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Extra resources for Mechanisms of Lymphocyte Activation and Immune Regulation VII: Molecular Determinants of Microbial Immunity

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Preliminary results indicate that a response by DETC in'areas immediately surrounding the wound can be detected. Changes in morphology and cell distribution are accompanied by localized secretion of cytokines. Further studies are in progress to determine the extent to which these cells participate in wound repair. 2. Inflammatory Bowel Disease. 35 . The immune system has been implicated in IBD and many patients can be treated with broadly immunosuppressive drugs with some success. However, long-term immunosuppression is associated with toxic side effects.

Carretero M, Cantoni C, Bellon T, Bottino C, Biassoni R, Rodriguez A, Perez-Villar JJ, Moretta L, Moretta A, Lopez-Botet M: The CD94 and NKG2-A C-type lectins covalently assemble to form a natural killer cell inhibitory receptor for HLA class I molecules. Eur J Immunol 27: 563-567, 1997. 21. Rojo S, Burshtyn DN, Long EO, Wagtmann N: Type I transmembrane receptor with inhibitory function in mouse mast cells and NK cells. J Immunol 158: 9-12, 1997. 22. Katz HR, Vivier E, Castells MC, McCormick MJ, Chambers JM, Austen KF: Mouse mast cell gp49B I contains two immunoreceptor tyrosine-based inhibition motifs and suppresses mast cell activation when coligated with the high-affinity Fc receptor for IgE.

O. Long 40. Vance RE, Tanamachi OM, Hanke T, Raulet DH: Cloning of a mouse homolog ofCD94 extends the family of C-type lectins on murine natural killer cells. Eur J Immunol 27: 3236--3241, 1997. 41. Yokoyama WM, Seaman WE: The Ly-49 and NKR-PI gene families encoding lectin-like receptors on natural killer cells: the NK gene complex. Annu Rev Immunol II: 613-635, 1993. 42. Mason LH, Anderson SK, Yokoyama WM, Smith HRC, Winkler-Pickett R, Ortaldo JR: The Ly-49D receptor activates murine natural killer cells.

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