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Extra resources for Chemical Structure–Biological Activity Relationships: Quantitative Approaches. Proceedings of the 3rd Congress of the Hungarian Pharmacological Society, Budapest, 1979

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Hirvonen, O . Ylikorkala, S. Nummi, P. Virkkunen, T . Ranta, U. Alapiessa and R. Vihko (1977), Contraception 16, 51. J. de Visser, E. P. de Jongh, J. d. J. Zeelen (1975), Acta Endocrinol. (Copenhagen) Suppl. 199, 405. U. D. B. Harding (1978), J. Health 4, 229. J. A. Keverling Buisman editor, Elsevier, Amsterdam, 147-160. , 1970). CH3COOCH2CH 2N+(CH ) 3 3 This classical model has been found to be successful in understanding of the general features of cholinesterase specificity and was used in design of new physiologically active compounds that react with these enzymes.

19 131 (1976) (8) G. M. Everett, R. K. Richards: J. Pharmacol. exptl. Ther. 81 402 (1944) (9) F. Darvas, B. Bord~s, M. Tiiske and Magda KovUcs: Magy, Kem. Lar. 33 627 (1978) (10) G. Swinyard: J. Pharmacol. exp. Ther. 106 319 (1952) (11) R. Benzinger, D. Hane: Arch. Int. Pharmacodyn. 167 245 (1967) (12) J. Borst', M. Cs~nyi, I. L~z iir: Arch. Int. Pharmacodyn, 124 1 (1960) (13) C. K. Nielsen, M. P. Magnussen, E. Kampmann, and H. H. Frey: Arch. Int. Pharmacodyn. 2 170 (1967) (14) J, T. Litchfield,Jr, F.

106 319 (1952) (11) R. Benzinger, D. Hane: Arch. Int. Pharmacodyn. 167 245 (1967) (12) J. Borst', M. Cs~nyi, I. L~z iir: Arch. Int. Pharmacodyn, 124 1 (1960) (13) C. K. Nielsen, M. P. Magnussen, E. Kampmann, and H. H. Frey: Arch. Int. Pharmacodyn. 2 170 (1967) (14) J, T. Litchfield,Jr, F. Wilcoxon: J. Pharm, Exptl. Ther. 95, 99 (1949) (15) W. P. Purcel, G. E. Bass, J. M. Clayton: Strategy of drug design: a guide to biological activity. Wiley-Interscience, New York, 1973 (16) Design of Benzodiazepines.

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