By John D. Robertson, Joya Chandra, Vladimir Gogvadze (auth.), Patrick M. Dansette, Robert Snyder, Marcel Delaforge, G. Gordon Gibson, Helmut Greim, David J. Jollow, Terrence J. Monks, I. Glenn Sipes (eds.)
This quantity provides a dialogue of the organic results produced following the metabolism of xenobiotic chemical compounds to chemically reactive metabolites, i.e., poisonous and carcinogenic results, which were the root of all 5 prior volumes during this sequence. particularly, this quantity devotes sections to structure-activity relationships, contemporary advances within the knowing of the chemistry of reactive metabolites, and the iteration and task of reactive oxygen species with detailed emphasis on nitric oxide. There also are segments on DNA harm by way of reactive metabolites and DNA fix, tissue particular responses to BRIs, and human wellbeing and fitness results of BRIs. The papers that include this quantity have been submitted by means of international classification scientists who have been in attendance on the Symposium on organic Reactive Intermediates VI on the Université René Descartes, July 16-20, 2000.