Download Cancer and Pregnancy by Tuan A. Dinh, David P. Warshal (auth.), Eytan R. Barnea MD, PDF

By Tuan A. Dinh, David P. Warshal (auth.), Eytan R. Barnea MD, FACOG, Eric Jauniaux MD, PhD, Peter E. Schwartz MD, FACOG (eds.)

Cancer and Pregnancy covers the medical demanding situations to diagnosing and treating malignancies within the pregnant sufferer; in spite of the fact that, the e-book additionally exhibits how an figuring out of the typical beneficial properties of either procedures (rapid mobile proliferation) could lead to novel anti-cancer remedies. The ebook might be learn by means of obstetricians and gynaecologists, scientific oncologists, replica experts, and people enthusiastic about research of improvement, biology, toxicology, immunology, in addition to melanoma research.

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Example text

Ifbleeding does occur, it may be controlled with 3 or 4 silver nitrate sticks applied directly to the biopsy site. If the results of cervical biopsies are consistent with the recent Pap smear, patients with cervical dysplasia may be followed with smears repeated every third month. For patients without evidence of progressive disease, repeat colposcopy and Pap smear should be performed 8 to 12 weeks postpartum. Appropriate follow-up is important, as one study indicates that the colposcopic impression oflow grade lesions may underestimate disease severity and that more advanced lesions, such as carcinoma-in-situ (CIS) persists more frequently in pregnant women.

Although rare, this situation is perhaps one of the most difficult to be encountered by the breast multi-disciplinary team and presents complex dilemmas to the obstetric team: it is vital that we collect more facts. Pathology The pathology of pregnancy-associated breast cancer in many ways resembles that of non-pregnant premenopausal women. Although one recent study (Bonnier et al. 1997) reports an excess of inflammatory breast cancer, most other studies report the incidence of the inflammatory type of tumour as 2 to 3% (Clark and Reid 1978).

3. FNA of fibroadenoma in pregnancy. The breast epithelium shows nuclear pleomorphism. Mag x 600 (oil immersion). Cytology courtesy of Dr GKocjan, University College London Prognosis Breast cancer survivors who decide to become pregnant may ultimately have a better outlook (Von Schoultz et al. 1995). Clark and Reid (1978) found that over half of those who became pregnant were alive at 15 years compared to only 35% of controls. They also found that the longer the time interval between diagnosis and pregnancy, the better the prognosis, and multiparous women did best of all.

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