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By Malcolm Carruthers

Simply what's the andropause? even though reputation of the andropause inspiration via the clinical group is transforming into, it's nonetheless a hotly debated factor. yet as a hectic clinician you will have sufferers to regard and also you desire details. So the place are you able to locate the data you must comprehend, diagnose, and deal with this situation? Androgen Deficiency within the grownup Male: factors, analysis and therapy distills the data received through writer Dr. Malcolm Carruthers in his 25 years of analysis and scientific adventure in diagnosing and treating the andropause right into a finished, targeted scientific resource.

Dr. Carruthers files the historical past of the hunt for testosterone remedy from antiquity to the awarding of the Nobel Prize to Adolf Butenandt and Leopold Ruzicka for synthesizing testosterone and patenting its creation a few 4,000 years later. He discusses the reasons of androgen deficiency, the male menopause or andropause, and up to date advances in its prognosis. The textual content contains stories of the literature in each one part and a fund of bibliographic references gleaned from the author's years of study during this box. this mix of gains makes Androgen Deficiency within the grownup Male: explanations, analysis and remedy a useful and useful medical advisor, an entire and precise reference quantity, and a cohesive and readable textbook.

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Additional resources for Androgen deficiency in the adult male : causes, diagnosis, and treatment

Example text

When the level of testosterone is adequate for the body’s needs, the gonadotropins fall to a low level. 30 ANDROGEN DEFICIENCY IN THE ADULT MALE Lacking sensitive blood assays, they had to extract a 12-h overnight sample of each man’s urine, inject the extract into immature female rats and measure the increase in weight of their ovaries caused by the gonadotropins in the sample. This simple biological test gave surprisingly clear-cut results. The urine of normal men, or those whose symptoms were due to anxiety or neurosis, showed virtually no gonadotropin activity in the urine.

This report foreshadowed the damaging influence of steroid abuse by athletes on the medical and public image of testosterone treatment. TWENTIETH CENTURY Although ‘organotherapy’ using extracts of different glands, particularly the thyroid and adrenal, continued to be the subject of much speculation and experimentation, it soon became clear that testicular extracts were not sufficiently powerful to have the hoped-for and much publicized effects originally claimed. This was because the minute amount of testosterone produced in the testis is continuously being swept away into the bloodstream, and is not stockpiled in the gland.

8 years and for men approximately 48 to 50 years . . Again, because of the prevalent belief that men do not have a climacteric period (which has been based on cessation of menstruation in women) the condition has probably been overlooked or ignored in men. The most prominent symptoms he described were loss of potency and libido, but in addition he mentions that, as with women, he observed: intense subjective nervousness, definite emotional instability characterised by irritability, sudden change in mood, decreased memory and ability for mental concentration, decreased interest in the usual activities, a desire to be left alone, and depression and crying.

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